HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl 4-(2-oxo-4-pyridin-4-ylimidazolidin-1-yl)piperidine-1-carboxylate → 1-Piperidin-4-yl-4-pyridin-4-ylimidazolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl 4-(2-oxo-4-pyridin-4-ylimidazolidin-1-yl)piperidine-1-carboxylate | HCID 68565475 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-Piperidin-4-yl-4-pyridin-4-ylimidazolidin-2-one | HCID 57979568 | — |
Reaction Steps
A solution of benzyl 4-(2-oxo-4-pyridin-4-ylimidazolidin-1-yl)piperidine-1-carboxylate (55 mg, 0.145 mmol) in ethanol (15 mL) was hydrogenated at 1 atm hydrogen over palladium on carbon (50 mg). After 16 h, the reaction was filtered and concentrated to give the title product. MS 247.2 (M+1)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07632832B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-bec02413f90948d0b9ecfe98d3532c6c |
| Source note | uspto-grants-2009_12 |