2',4'-Dihydroxyacetophenone → 1-[2,4-Dihydroxyphenyl]-3-[4-carboxydimethylmethyloxyphenyl]prop-2-en-1-one

HRID 1867669Notes

Reaction equation

[OH:1][C:2]1[CH:7]=[C:6]([OH:8])[CH:5]=[CH:4][C:3]=1[C:9](=[O:11])[CH3:10].C([O:14][C:15]([C:17]1[C:24]([CH3:25])=[CH:23][C:20]([CH:21]=O)=[C:19]([O:26][CH3:27])[C:18]=1[CH3:28])=[O:16])C>>[OH:1][C:2]1[CH:7]=[C:6]([OH:8])[CH:5]=[CH:4][C:3]=1[C:9](=[O:11])[CH:10]=[CH:21][C:20]1[CH:23]=[C:24]([CH3:25])[C:17]([C:15]([OH:16])=[O:14])=[C:18]([CH3:28])[C:19]=1[O:26][CH3:27]

Participants

Reactant 2

HCID 69902',4'-Dihydroxyacetophenone

HCID 865999714-Ethyloxycarbonyidimethylmethyloxybenzaldehyde2×

Product 1

HCID 865999781-[2,4-Dihydroxyphenyl]-3-[4-carboxydimethylmethyloxyphenyl]prop-2-en-1-one

Procedure

This compound was synthesized from 2′,4′-dihydroxyacetophenone and 4-ethoxycarbonyldimethylmethyloxybenzaldehyde (starting material 4) according to general method 2 described earlier.

Sources & evidence

ORD record: ord-14029c834d87423096efe67df5ca6143
Source dataset: uspto-grants-2009_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07632870B2

Reaction notes

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