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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1867677Generated: November 3, 2026

(2S)-2-(((tert-butoxy)carbonyl)amino)-3-methoxypropanoic acid → HCID 86616946, compound

https://huagongshe.com/reaction/1867677

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S)-2-(((tert-butoxy)carbonyl)amino)-3-methoxypropanoic acidHCID 7016354—
ReactantHCID 11691173HCID 11691173—
ReactantN-[(1,1-Dimethylethoxy)carbonyl]-O-methyl-L-homoserineHCID 15058461—
ProductHCID 86616946HCID 86616946—

Reaction Steps

The N2,O-dimethyl-L-homoserinamide used as starting material was prepared by methylating N-(tert-butoxycarbonyl)-O-methyl-L-homoserine using an analogous method to that described in Example 7 for the methylation of N-(tert-butoxycarbonyl)-O-methyl-L-serine, to give N-(tert-butoxycarbonyl)-N,O-dimethyl-L-homoserine; 1H NMR spectrum: (DMSO d6, 100° C.) 1.40 (s, 9H), 1.91 (m, 1H), 2.09 (m, 1H), 2.75 (s, 3H), 3.24 (s, 3H), 3.34 (m, 2H), 4.44 (m, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07632840B2
Source datasetuspto-grants-2009_12
ORD IDord-93074dd4f2074680aac2ced2b85ccef8
Source noteuspto-grants-2009_12