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HRID1867860

反应详情

EQUATION

反应方程式

HRID 1867860 的结构方程式

REACTANTS

反应物

2
结构：C[C@@H]1CCCN1C[C@@H]1CCCN1
HCID46911921

(2R)-2-Methyl-1-{[(2S)-pyrrolidin-2-yl]methyl}pyrrolidine

C10H20N2

结构：COc1cccc(-c2ccc(C(=O)O)cc2)n1
HCID53426335

4-(6-Methoxypyridin-2-yl)benzoic acid

C13H11NO3

PRODUCTS

生成物

1
结构：COc1cccc(-c2ccc(C(=O)N3CCC[C@H]3CN3CCC[C@H]3C)cc2)n1
HCID57980055

未命名化合物

收率 76%

PROCEDURE

实验过程

The title compound is prepared in a manner substantially analogous to General Procedure B′ using 4-(6-Methoxy-pyridin-2-yl)-benzoic acid (573 mg, 2.5 mmol) and 2-(R)-methyl-1-(2-(S)-pyrrolidinylmethyl)pyrrolidine (337 mg, 2.0 mmol) to give 580 mg (76% yield). MS (ES+) 380.2 (M+H)+

WORKUP

后处理

  1. customto give 580 mg (76% yield)