HCID 15131407, compound → 2-Propenoic acid, 2-isocyanatoethyl ester
Reaction equation
Cl[CH2:2][CH2:3][C:4]([O:6][CH2:7][CH2:8][N:9]=[C:10]=[O:11])=[O:5]>C1(C)C=CC=CC=1>[C:4]([O:6][CH2:7][CH2:8][N:9]=[C:10]=[O:11])(=[O:5])[CH:3]=[CH2:2]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 50 °C
Procedure
A three-necked flask was charged with 500 ml of toluene, 60 g (0.34 mol) of (2-isocyanatoethyl) 3-chloropropionate obtained in Synthesis Example 2, and 200 g of a dried strongly basic ion-exchange resin, followed by heating at 50° C. for 6 hours with stirring. After cooling to room temperature, the ion-exchange resin was filtered off. Subsequently, the toluene was evaporated, and the remainder was distilled (at 62-67° C. and 0.7 kPa) to yield 41 g (0.29 mol) of acryloyloxyethyl isocyanate (boiling point: 200° C.) (86% yield). The hydrolyzable chlorine concentration was 270 ppm.
Workup
- customobtained in Synthesis Example 2, and 200 g of
- customa dried strongly basic ion-exchange resin
- temperatureAfter cooling to room temperature
- filtrationthe ion-exchange resin was filtered off
- customSubsequently, the toluene was evaporated
- distillationthe remainder was distilled (at 62-67° C. and 0.7 kPa)
Sources & evidence
- ORD record
- ord-8f8981e0942f49e481920389afc6586d
- Source dataset
- uspto-grants-2009_12
- Patent number
- US07632965B2
Reaction notes
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