Trifluoroacetic acid → HCID 57980850, compound

Participants

Reaction Steps

A solution of thiophene-2-sulfonic acid 2-tert-butoxycarbonylaminobenzo-thiazol-6-yl ester (intermediate 30) (1.5 g, 3.63 mmol) and trifluoroacetic acid (15 ml, 196 mmol) in 15 ml of dichloromethane and 600 μl of water is stirred for 2 hours at room temperature. The reaction medium is concentrated to dryness to give 900 mg of thiophene-2-sulfonic acid 2-aminobenzothiazol-6-yl ester in the form of the trifluoroacetic acid salt (oil) in a yield of 76%.

Provenance & Evidence