2,3-Dichloropyridine → HCID 68554029, compound

HRID 1868033Notes

Reaction equation

HRID 1868033 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([S:9]([CH:12]2[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]2)(=[O:11])=[O:10])[CH:5]=[CH:6][C:7]=1[Cl:8].Cl[C:19]1[C:24]([Cl:25])=[CH:23][CH:22]=[CH:21][N:20]=1>>[Cl:25][C:24]1[C:19]([N:15]2[CH2:16][CH2:17][CH:12]([S:9]([C:4]3[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=3)(=[O:11])=[O:10])[CH2:13][CH2:14]2)=[N:20][CH:21]=[CH:22][CH:23]=1

Participants

3

Reactant 2

HCID 169882,3-DichloropyridineHCID 223974994-(3,4-Dichloro-benzenesulfonyl)-piperidine

Product 1

HCID 68554029HCID 68554029, compoundYield 33%

Procedure

Using the procedure from Example 7A, Step 7E, 4-[(3,4-dichlorophenyl)sulfonyl]piperidine (200 mg, 0.68 mmol) was reacted with 2,3-dichloropyridine (201 mg, 1.36 mmol) to afford the title compound (90 mg), a white solid, in 33% yield.

Sources & evidence

ORD record
ord-a0c3d7a78be440e3b4594f5f93a59e96
Source dataset
uspto-grants-2009_12
Patent number
US07632838B2

Reaction notes

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