2-Chloro-3-nitropyridine → HCID 68555016, compound

HRID 1868035Notes

Reaction equation

HRID 1868035 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([S:9]([CH:12]2[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]2)(=[O:11])=[O:10])[CH:5]=[CH:6][C:7]=1[Cl:8].Cl[C:19]1[C:24]([N+:25]([O-:27])=[O:26])=[CH:23][CH:22]=[CH:21][N:20]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([S:9]([CH:12]2[CH2:17][CH2:16][N:15]([C:19]3[C:24]([N+:25]([O-:27])=[O:26])=[CH:23][CH:22]=[CH:21][N:20]=3)[CH2:14][CH2:13]2)(=[O:11])=[O:10])[CH:5]=[CH:6][C:7]=1[Cl:8]

Participants

3

Reactant 2

HCID 796132-Chloro-3-nitropyridineHCID 223974994-(3,4-Dichloro-benzenesulfonyl)-piperidine

Product 1

HCID 68555016HCID 68555016, compoundYield 99.9%

Procedure

Using the procedure from Example 7A, Step 7E, 4-[(3,4-dichlorophenyl)sulfonyl]piperidine (150 mg, 0.51 mmol) was reacted with 2-chloro-3-nitropyridine (97 mg, 0.61 mmol) to afford the title compound (212 mg), a yellow solid, in 74% yield.

Sources & evidence

ORD record
ord-257eddfd8acf4f5ea6d6ac43060a6828
Source dataset
uspto-grants-2009_12
Patent number
US07632838B2

Reaction notes

Loading…