HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dichloropyridine → 3-Chloro-2-[4-(2-naphthylsulfonyl)piperidin-1-yl]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dichloropyridine | HCID 16988 | — |
| Reactant | 4-(2-Naphthylsulfonyl)piperidine | HCID 22721937 | — |
| Product | 3-Chloro-2-[4-(2-naphthylsulfonyl)piperidin-1-yl]pyridine | HCID 68555010 | 48.8% |
Reaction Steps
Using the procedure from Example 7A, Step 7E, 4-(2-naphthylsulfonyl)piperidine (Example 11, Step 3, 175 mg, 0.63 mmol) was reacted with 2,3-dichloropyridine (188 mg, 1.3 mmol) to afford the title compound (119 mg), a white solid, in 48% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07632838B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-d248e8b26c264665aec390e14c85927c |
| Source note | uspto-grants-2009_12 |