HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4,5-Trichloropyridine → 3,5-Dichloro-4-[4-(2-naphthylsulfonyl)piperidin-1-yl]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4,5-Trichloropyridine | HCID 3786531 | — |
| Reactant | 4-(2-Naphthylsulfonyl)piperidine | HCID 22721937 | — |
| Product | 3,5-Dichloro-4-[4-(2-naphthylsulfonyl)piperidin-1-yl]pyridine | HCID 68554101 | 12.1% |
Reaction Steps
Using the procedure from Example 7A, Step 7E, 4-(2-naphthylsulfonyl)piperidine (130 mg, 0.51 mmol) was reacted with 3,4,5-trichloropyridine (182 mg, 1.0 mmol) to afford the title compound (26 mg), a white solid, in 12% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07632838B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-abc6f01c8c4c494da8093a42dbfdcbbf |
| Source note | uspto-grants-2009_12 |