HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-3-nitropyridine → 2-[4-(2-Naphthylsulfonyl)piperidin-1-yl]-3-nitropyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-3-nitropyridine | HCID 79613 | — |
| Reactant | 4-(2-Naphthylsulfonyl)piperidine | HCID 22721937 | — |
| Product | 2-[4-(2-Naphthylsulfonyl)piperidin-1-yl]-3-nitropyridine | HCID 68555048 | 73% |
Reaction Steps
Using the procedure from Example 7A, Step 7E, 4-(2-naphthylsulfonyl)piperidine (130 mg, 0.51 mmol) was reacted with 2-chloro-3-nitropyridine (158 mg, 1.0 mmol) to afford the title compound (148 mg), a yellow solid, in 73% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07632838B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-5ccd8dc9b6e04618bd229aa8840e15db |
| Source note | uspto-grants-2009_12 |