2,3-Dichloropyridine → HCID 68554716, compound

HRID 1868051Notes

Reaction equation

HRID 1868051 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([CH:11]1[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]1)(=[O:10])=[O:9].Cl[C:18]1[C:23]([Cl:24])=[CH:22][CH:21]=[CH:20][N:19]=1>>[Cl:24][C:23]1[C:18]([N:14]2[CH2:15][CH2:16][CH:11]([S:8]([C:3]3[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=3[Cl:1])(=[O:9])=[O:10])[CH2:12][CH2:13]2)=[N:19][CH:20]=[CH:21][CH:22]=1

Participants

3

Reactant 2

HCID 169882,3-DichloropyridineHCID 53417650HCID 53417650, compound

Product 1

HCID 68554716HCID 68554716, compoundYield 51.1%

Procedure

Using the procedure from Example 7A, 4-[(2-chlorophenyl)sulfonyl]piperidine (150 mg, 0.58 mmol) was reacted with 2,3-dichloropyridine (173 mg, 1.16 mmol) to afford the title compound (110 mg), a white solid, in 51% yield.

Sources & evidence

ORD record
ord-c13999e75e904b58a97da9b97f64532f
Source dataset
uspto-grants-2009_12
Patent number
US07632838B2

Reaction notes

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