HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 68554195, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 2-Chloro-3-fluoropyridine | HCID 2782791 | — |
| Reactant | 4-[(3-Chlorophenyl)sulfonyl]piperidine | HCID 53417698 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 68554195 | HCID 68554195 | 7% |
Reaction Steps
Using the procedure from Example 7A, 4-[(3-chlorophenyl)sulfonyl]piperidine (100 mg, 0.38 mmol) was reacted with 2-chloro-3-fluoropyridine (100 mg, 0.76 mmol), DIEA (0.2 ml, 1.14) and 1,4-dioxane (0.3 ml) to afford the title compound (9 mg), a yellow solid, in 7% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07632838B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-875b0908e1d349ca9ac09a53db105134 |
| Source note | uspto-grants-2009_12 |