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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1868059Generated: November 1, 2026

Diisopropylethylamine → HCID 68554195, compound

https://huagongshe.com/reaction/1868059

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
Reactant2-Chloro-3-fluoropyridineHCID 2782791—
Reactant4-[(3-Chlorophenyl)sulfonyl]piperidineHCID 53417698—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 68554195HCID 685541957%

Reaction Steps

Using the procedure from Example 7A, 4-[(3-chlorophenyl)sulfonyl]piperidine (100 mg, 0.38 mmol) was reacted with 2-chloro-3-fluoropyridine (100 mg, 0.76 mmol), DIEA (0.2 ml, 1.14) and 1,4-dioxane (0.3 ml) to afford the title compound (9 mg), a yellow solid, in 7% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07632838B2
Source datasetuspto-grants-2009_12
ORD IDord-875b0908e1d349ca9ac09a53db105134
Source noteuspto-grants-2009_12