HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromotoluene → 4-[(4-Tert-butylphenyl)sulfonyl]-1-(2-methylphenyl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromotoluene | HCID 7236 | — |
| Reactant | 4-[(4-Tert-butylphenyl)sulfonyl]piperidine | HCID 18538636 | — |
| Product | 4-[(4-Tert-butylphenyl)sulfonyl]-1-(2-methylphenyl)piperidine | HCID 68554826 | 44.1% |
Reaction Steps
Using the procedure from Example 7A, 4-[(4-tert-butylphenyl)sulfonyl]piperidine (100 mg, 0.36 mmol) was reacted with 2-bromotoluene (53 μl, 0.43 mmol) to afford the title compound (59 mg), a yellow solid, in 44% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07632838B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-e00085e35fc64b7c92edff9ab278ba6a |
| Source note | uspto-grants-2009_12 |