1,2-Dimethoxyethane → Tert-butyl 4-(carbamothioylmethoxy)piperidine-1-carboxylate

HRID 186822Notes

Reaction equation

HRID 186822 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][CH2:15][C:16]([NH2:17])=[O:18])[CH2:12][CH2:13]1.[CH2:41]([CH2:42][O:43][CH3:44])[O:45][CH3:46].[CH3:19][O:20][c:21]1[cH:22][cH:23][c:24]([P:25]2(=[S:28])[S:26][P:27]([c:29]3[cH:30][cH:31][c:32]([O:33][CH3:34])[cH:35][cH:36]3)(=[S:37])[S:38]2)[cH:39][cH:40]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][CH2:15][C:16]([NH2:17])=[S:28])[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 80711,2-DimethoxyethaneHCID 87949Lawesson's reagentHCID 578567294-Carbamoylmethoxypiperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 45496681Tert-butyl 4-(carbamothioylmethoxy)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-e32235ac791146d8889df3a309c2afe2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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