HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylthiophene-2-boronic acid → 4-Amino-2-(4-methyl-thiophen-2-yl)thieno[3,2-c]pyridine-7-carboxylic acid amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylthiophene-2-boronic acid | HCID 2734373 | — |
| Reactant | 4-Amino-2-Bromothieno[3,2-C]pyridine-7-Carboxamide | HCID 58840713 | — |
| Product | 4-Amino-2-(4-methyl-thiophen-2-yl)thieno[3,2-c]pyridine-7-carboxylic acid amide | HCID 58840720 | — |
Reaction Steps
19 was prepared from 4-amino-2-bromo-thieno[3,2-c]pyridine-7-carboxylic acid amide 17 and 4-methyl-2-thiopheneboronic acid according to the general procedure described in Example 2. 1H NMR (400 MHz, d6-DMSO) δ: 2.25 (s, 3H), 7.29 (s, 1H), 7.36 (s, 1H), 7.80 (br s, 1H), 8.14 (s, 1H), 8.40 (br s, 1H), 8.46 (s, 1H). MS (EI) m/z (M+H+) 290.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07635695B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-7def02479f2a4d40800e8311710de7c7 |
| Source note | uspto-grants-2009_12 |