HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(Phenylamino)-4-(trifluoromethyl)pyrimidine-5-carboxylic acid → 2-(Phenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid cyclopentylmethyl-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(Phenylamino)-4-(trifluoromethyl)pyrimidine-5-carboxylic acid | HCID 16719550 | — |
| Edukt | Cyclopentylmethanamine hydrochloride | HCID 18784136 | — |
| Produkt | 2-(Phenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid cyclopentylmethyl-amide | HCID 57982678 | 82,9% |
Reaktionsschritte
In a manner similar to Reference Example 1 (c), 2-(Phenylamino)-4-trifluoromethyl-pyrimidine-5-carboxylic acid (30 mg) and cyclopentylmethylamine hydrochloride (21 mg) afforded the title compound (32 mg) after purification by trituration with diethylether.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07635701B2 |
| Quelldatensatz | uspto-grants-2009_12 |
| ORD ID | ord-a1cdb7b6234b4ae399a9a356e86a951a |
| Quellennotiz | uspto-grants-2009_12 |