Tert-Butylamine → HCID 11534361, compound

Participants

Reaction Steps

3′,4′-Dibenzyloxy-6-(2,3-epoxy-propoxy)-flavone, 30 (1.5 g, 3 mmol) and tert-butyl amine (0.96 mL, 9 mmol) in dry methanol (125 mL) were reacted in a similar manner to that described under 34 to afford 39. Yield 1.5 g (89%); mp 156-157° C.; MS (FAB) 580 (M++1); IR (KBr) 3404, 1621; 1H NMR (200 MHz, CDCl3) δ 7.51-7.26 (m, 15H), 6.97 (d, J=8.9 Hz, 1H), 6.62 (s, 1H), 5.22 (s, 2H), 5.20 (s, 2H), 4.26-4.22 (m, 1H), 4.14-4.10 (m, 2H), 3.07-2.86 (m, 2H), 1.29 (s, 9H). Analysis Calcd for C36H37NO6: C, 74.59; H, 6.43; N, 2.42. Found: C, 74.61; H, 6.62; N, 2.36.

Provenance & Evidence