HRID18686

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccccc1CCC(=O)Nc1sc2c(c1C#N)CCN(C(=O)OCCOC(C)=O)C2

HCID11857434

未命名化合物

PRODUCTS

生成物

结构：COc1ccccc1CCC(=O)Nc1sc2c(c1C#N)CCN(C(=O)OCCO)C2

HCID11857437

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID14798

Sodium Hydroxide

HNaO

PROCEDURE

实验过程

3-Cyano-2-[3-(2-methoxy-phenyl)-propionylamino]-4,7-dihydro-5H-thieno[2,3-c]pyridine-6-carboxylic acid 2-acetoxy-ethyl ester (Example 31) is stirred in 1N NaOH over night at room temperature. After acidification with aqueous HCl the precipitated product is filtered off and recristalized from ethanol.

WORKUP

后处理

filtrationAfter acidification with aqueous HCl the precipitated product is filtered off