1,1-Dibromoethane → HCID 69032853, compound

Participants

Reaction Steps

This compound (57) was prepared from 3′,4′-dibenzyloxy-7-hydroxy-flavone, 23 (2.3 g, 5.1 mmol), dibromo ethane (1.7 mL, 20.4 mmol) and potassium carbonate (3.5 g, 25.5 mmol) in dry dimethyl formamide (90 mL) using the identical procedure as described for 56. Yield 2.1 g (74%); mp 167-168° C.; MS (FAB) 557/559 (M++1); IR (KBr) 1626; 1H NMR (200 MHz, CDCl3) δ 8.12 (d, J=8.8 Hz, 1H), 7.50-7.32 (m, 12H), 7.01 (d, J=9.1 Hz, 1H), 6.92 (dd, J=8.9 Hz, 2.2 Hz, 1H), 6.91 (s, 1H), 6.60 (s, 1H), 5.24 (s, 4H), 4.39 (t, J=6.2 Hz, 2H), 3.69 (t, J=6.3 Hz, 2H).

Provenance & Evidence