1,1-Dibromoethane → HCID 69033169, compound

Participants

Reaction Steps

This compound (58) was prepared from 7-hydroxy-3′,4′,5′-trimethoxy-flavone, 25 (2.3 g, 7 mmol), dibromo ethane (3 mL, 35 mmol) and potassium carbonate (2.9 g, 21 mmol) in dry dimethyl formamide (120 mL) using the identical procedure as described for 56. Yield 2.1 g (68%); mp 184-185° C.; MS (FAB) 435/437 (M++1); IR (KBr) 1631; 1H NMR (200 MHz, CDCl3) δ 8.15 (d, J=9.3 Hz, 1H), 7.10 (s, 2H), 7.01 (d, J=7.8 Hz, 1H), 6.99 (s, 1H), 6.71 (s, 1H), 4.43 (t, J=6.2 Hz, 2H), 3.96 (s, 6H), 3.93 (s, 3H), 3.70 (t, J=6.2 Hz, 2H).

Provenance & Evidence