Potassium Carbonate → HCID 69030799, compound

Participants

Reaction Steps

This compound (59) was prepared from 7-hydroxy-3′,4′,5′-trimethoxy-flavone, 25 (3.3 g, 10 mmol), dibromo propane (3 mL, 30 mmol) and potassium carbonate (2.7 g, 20 mmol) in dry dimethyl formamide (120 mL) using the identical procedure as described for 56. Yield 3.1 g (69%); mp 156-157° C.; MS (FAB) 449/451 (M++1); IR (KBr) 1629; 1H NMR (200 MHz, CDCl3) δ 8.13 (d, J=9.4 Hz, 1H), 7.11 (s, 2H), 7.01-6.97 (m, 2H), 6.70 (s, 1H), 4.25 (t, J=5.8 Hz, 2H), 3.96 (s, 6H), 3.93 (s, 3H), 3.64 (t, J=6.3 Hz, 2H), 2.39 (q, J=6.1 Hz, 2H).

Provenance & Evidence