Potassium Carbonate → HCID 69030155, compound

Participants

Reaction Steps

This compound (60) was prepared from 3′,5′-dimethoxy-7-hydroxy-flavone, 26 (1.1 g, 3.7 mmol), dibromo propane (1.9 mL, 18.5 mmol) and potassium carbonate (1.5 g, 11.1 mmol) in dry dimethyl formamide (100 mL) using the identical procedure as described for 56. Yield 1.1 g (74%); mp 173-174° C.; MS (FAB) 419/421 (M++1); IR (KBr) 1631; 1H NMR (200 MHz, DMSO-d6) δ 7.88 (d, J=8.8 Hz, 1H), 7.35 (d, J=2.1 Hz, 1H), 7.17 (d, J=2.1 Hz, 2H), 7.02 (dd, J=8.9 Hz, 2.2 Hz, 1H), 6.98 (s, 1H), 6.66 (s, 1H), 4.19 (t, J=5.9 Hz, 2H), 3.79 (s, 6H), 3.64 (t, J=6.4 Hz, 2H), 2.26 (q, J=6.2 Hz, 2H).

Provenance & Evidence