Potassium Carbonate → HCID 69029207, compound

Participants

Reaction Steps

This compound (61) was prepared from 3′,4′-dimethoxy-7-hydroxy-flavone, 27 (3 g, 10 mmol), dibromo propane (4 mL, 39.2 mmol) and potassium carbonate (2.8 g, 20 mmol) in dry dimethyl formamide (150 mL) using the identical procedure as described for 56. Yield 3.4 g (80%); mp 148-149° C.; MS (FAB) 419/421 (M++1); IR (KBr) 1630; 1H NMR (200 MHz, CDCl3) δ 8.12 (d, J=9.5 Hz, 1H), 7.53 (dd, J=8.5 Hz, 2.0 Hz, 1H), 7.36 (d, J=1.9 Hz, 1H), 6.99-6.95 (m, 3H), 6.68 (s, 1H), 4.24 (t, J=5.8 Hz, 2H), 3.98 (s, 3H), 3.96 (s, 3H), 3.64 (t, J=6.3 Hz, 2H), 2.39 (q, J=6.1 Hz, 2H).

Provenance & Evidence