Trifluoroacetic acid → HCID 57983411, compound

Participants

Reaction Steps

1,1-Dimethylethyl N-((7-chloro-6-fluoro-4-hydroxy-1,1-dimethyl-2-oxo-naphthalen-3-yl)carbonyl)glycinate (200 mg, 503 μmol) was reacted with TFA (2 mL) at ambient temperature for 30 minutes. The mixture was concentrated, precipitated with hexanes, filtered, washed with hexanes, and dried in a vacuum oven to give the title compound (139 mg) as a white solid. MS m/e=342 (M+H)+. Calculated for C15H13NO5 341.05.

Provenance & Evidence