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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1869022Generated: October 31, 2026

HCID 67351076, compound → 4-[(4-Hydroxy-2-methylphenyl)methyl]-5-isopropyl-3-(2,3,4,6-tetra-O-pivaloyl-beta-D-glucopyranosyloxy)-1H-pyrazole

https://huagongshe.com/reaction/1869022

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67351076HCID 67351076—
CatalystHCID 178418390HCID 178418390—
SolventTetrahydrofuranHCID 8028—
Product4-[(4-Hydroxy-2-methylphenyl)methyl]-5-isopropyl-3-(2,3,4,6-tetra-O-pivaloyl-beta-D-glucopyranosyloxy)-1H-pyrazoleHCID 6853735899.8%

Reaction Steps

4-[(4-Benzyloxy-2-methylphenyl)methyl]-5-isopropyl-3-(2,3,4,6-tetra-O-pivaloyl-β-D-glucopyranosyloxy)-1H-pyrazole (5 g) was dissolved in tetrahydrofuran (18 mL). To the solution was added 10% palladium-carbon powder (500 mg), and the mixture was stirred at room temperature under a hydrogen atmosphere for 3 hours. The insoluble material was removed by filtration, and the solvent of the filtrate was removed under reduced pressure to give the title compound (4.45 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07635684B2
Source datasetuspto-grants-2009_12
ORD IDord-d892f70aa9814510ad07e7c35e42ed77
Source noteuspto-grants-2009_12