HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1869148Generated: October 30, 2026
Potassium Iodide → 2-{3-[2,6-Dichloro-4-(3,3-dichloro-allyloxy)-phenoxy]-propyl}-2-(4-fluoro-phenyl)-[1,3]dioxolane
https://huagongshe.com/reaction/1869148
Participants
| Role | Name | HCID | Charge |
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| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-(3-Chloropropyl)-2-(4-fluorophenyl)-1,3-dioxolane | HCID 2723778 | — |
| Reactant | 4-(3,3-Dichloro-2-propenyloxy)-2,6-dichlorophenol | HCID 11346738 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 2-{3-[2,6-Dichloro-4-(3,3-dichloro-allyloxy)-phenoxy]-propyl}-2-(4-fluoro-phenyl)-[1,3]dioxolane | HCID 86613087 | — |
Reaction Steps
2.0 g of 2-(3-chloro-propyl)-2-(4-fluoro-phenyl)-[1,3]dioxolane are added to a suspension of 2.36 g of 2,6-dichloro-4-(3,3-dichloro-allyloxy)-phenol, 1.7 g of potassium carbonate and 120 mg of potassium iodide in 50 ml of acetone. The mixture is then stirred for 48 hours at 60° C. The reaction mixture is concentrated and the residue is taken up in water and extracted with ethyl acetate. After concentration of the organic phase and purification over silica gel, 2-{3-[2,6-dichloro-4-(3,3-dichloro-allyloxy)-phenoxy]-propyl}-2-(4-fluoro-phenyl)-[1,3]dioxolane is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07638514B2 |
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| Source dataset | uspto-grants-2009_12 |
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| ORD ID | ord-83161661a247422c8e54442bf3390b6b |
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| Source note | uspto-grants-2009_12 |
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