1H-Pyrrolo[2,3-B]pyridine, 4-chloro-1-[(1,1-dimethylethyl)dimethylsilyl]- → HCID 57985899, compound

HRID 1869187Notes

Reaction equation

HRID 1869187 reaction equation
[CH3:1][C:2]1([CH3:26])[O:7][C:6](=[O:8])[CH:5]([CH:9]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:10]2[C:18]3[C:13](=[N:14][CH:15]=[CH:16][CH:17]=3)[NH:12][CH:11]=2)[C:4](=[O:25])[O:3]1.C([Si](C)(C)N1C2=NC=CC([Cl:41])=C2C=C1)(C)(C)C>>[Cl:41][C:17]1[CH:16]=[CH:15][N:14]=[C:13]2[NH:12][CH:11]=[C:10]([CH:9]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH:5]3[C:6](=[O:8])[O:7][C:2]([CH3:26])([CH3:1])[O:3][C:4]3=[O:25])[C:18]=12

Participants

3

Reactant 2

HCID 497590071H-Pyrrolo[2,3-B]pyridine, 4-chloro-1-[(1,1-dimethylethyl)dimethylsilyl]-HCID 68556789HCID 68556789, compound

Product 1

HCID 57985899HCID 57985899, compound

Procedure

5-[(4-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-phenyl-methyl]-2,2-dimethyl-[1,3]dioxane-4,6-dione was prepared following the procedure described for preparation of 2,2-dimethyl-5-[phenyl-(1H-pyrrolo[2,3-b]pyridin-3-yl)-methyl]-[1,3]dioxane-4,6-dione in example 1, using 1-(tert-butyl-dimethyl-silanyl)-4-chloro-1H-pyrrolo[2,3-b]pyridine.

Sources & evidence

ORD record
ord-06cd3b964b5a46e992a0347c44674e77
Source dataset
uspto-grants-2009_12
Patent number
US07638517B2

Reaction notes

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