HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Aminoquinoline → 1,1,1-Trifluoro-4-phenyl-2-[(quinolin-5-yl)iminomethyl]-4-methylpentan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Aminoquinoline | HCID 11911 | — |
| Reactant | 2-Hydroxy-4-methyl-4-phenyl-2-trifluoromethylpentanal | HCID 17989092 | — |
| Product | 1,1,1-Trifluoro-4-phenyl-2-[(quinolin-5-yl)iminomethyl]-4-methylpentan-2-ol | HCID 17989185 | — |
Reaction Steps
Analogously to Example 13, 120 mg of 2-hydroxy-4-methyl-4-phenyl-2-trifluoromethylpentanal and 61 mg of 5-aminoquinoline are converted into 95 mg of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07638515B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-fe7745141cfc4ac28c53ce5485ef5c46 |
| Source note | uspto-grants-2009_12 |