HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Amino-1,2-dihydroquinolin-2-one → 5-{[2-Hydroxy-4-methyl-4-phenyl-2-(trifluoromethyl)pentylidene]amino}quinolin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Amino-1,2-dihydroquinolin-2-one | HCID 15719078 | — |
| Reactant | 2-Hydroxy-4-methyl-4-phenyl-2-trifluoromethylpentanal | HCID 17989092 | — |
| Product | 5-{[2-Hydroxy-4-methyl-4-phenyl-2-(trifluoromethyl)pentylidene]amino}quinolin-2(1H)-one | HCID 17989208 | — |
Reaction Steps
Analogously to Example 13, 600 mg of 2-hydroxy-4-methyl-4-phenyl-2-(trifluoromethyl)pentanal and 337 mg of 5-aminoquinolin-2(1H)-one (52313) are converted into 570 mg of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07638515B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-b12bbb00601d4fbbaa8e53a52090f7fa |
| Source note | uspto-grants-2009_12 |