HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Indazol-4-amine, 1-methyl- → HCID 68682622, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Indazol-4-amine, 1-methyl- | HCID 153838 | — |
| Reactant | 4-(2-Methoxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentanal | HCID 17989098 | — |
| Catalyst | Titanium Tetrachloride | HCID 24193 | — |
| Product | HCID 68682622 | HCID 68682622 | 23.4% |
Reaction Steps
Analogously to Example 3, the corresponding imine is produced starting from 296 mg of 4-(2-methoxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentanal and 150 mg of 4-amino-1-methylindazole. By reaction of 100 mg of the imine with 0.5 ml of titanium tetrachloride, 100 mg of the title compound is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07638515B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-2120ce321d604d248a798cd98e426433 |
| Source note | uspto-grants-2009_12 |