Hydrochloric Acid → HCID 69062219, compound

Participants

Reaction Steps

0.5 g (0.69 mmol) (R)-1-(4-amino-3-chloro-5-trifluoromethyl-benzyl)-2-[4-(4-methyl-piperazin-1-yl)-piperidin-1-yl]-2-oxo-ethyl 4-(2-oxo-1,2,4,5-tetrahydro-1,3-benzodiazepin-3-yl)-piperidine-1-carboxylate are dissolved in 5 ml isopropanol at ambient temperature. After the addition of 95.2 μl hydrochloric acid (12.4 mol/l in ethanol) a white precipitate is formed spontaneously. After 12 hours at ambient temperature the precipitate formed is filtered off and dried at 70° C.

Provenance & Evidence