Tetrahydrofuran → HCID 11657654, compound

Participants

Reaction Steps

Sodium (1.5 mg, 0.07 mmol) was dissolved in methanol (1 ml). Bis(2,4,6-tri-O-acetyl-3-deoxy-3-(3,5-dimethoxybenzamido)-β-D-galactopyranosyl) sulfane 14 (11 mg, 0.012 mmol) was dissolved in methanol (1 ml) and the sodium methoxide solution was added. The mixture was stirred at room temperature for 3 h. After this time, a precipitate had appeared. THF (3 ml) was added, and the precipitate dissolved. Duolite C436 (H+) was added, and the mixture was stirred for 5 minutes. After this time, the mixture was filtered and concentrated in vacuo. The residue was purified by HPLC (gradient H2O→MeCN) to give bis(3-deoxy-3-(3,5-dimethoxybenzamido)-β-D-galactopyranosyl) sulfane 19 (4.7 mg, 58%). White solid;

Provenance & Evidence