(2-Fluoro-4-methoxyphenyl)methanol → 4-chloro-N-(5,5-difluoro-2-oxoazepan-3-yl)-N-[(2-fluoro-4-methoxyphenyl)methyl]benzenesulfonamide
Reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[NH:11][CH:12]2[C:13](=[O:21])[NH:14][CH2:15][CH2:16][C:17]([F:19])([F:20])[CH2:18]2)[cH:6][cH:7]1.[F:22][c:23]1[c:24]([CH2:31][OH:32])[cH:25][cH:26][c:27]([O:29][CH3:30])[cH:28]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[N:11]([CH:12]2[C:13](=[O:21])[NH:14][CH2:15][CH2:16][C:17]([F:19])([F:20])[CH2:18]2)[CH2:31][c:24]2[c:23]([F:22])[cH:28][c:27]([O:29][CH3:30])[cH:26][cH:25]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-aaf7fd65ae984e83af074ee2cdcd2f8c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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