HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-[(2,6-dichlorobenzoyl)amino]-3-(4-nitrophenyl)propanoate → Methyl 3-(4-aminophenyl)-2-[(2,6-dichlorobenzoyl)amino]propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-[(2,6-dichlorobenzoyl)amino]-3-(4-nitrophenyl)propanoate | HCID 57987623 | — |
| Catalyst | Platinum | HCID 23939 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 3-(4-aminophenyl)-2-[(2,6-dichlorobenzoyl)amino]propanoate | HCID 18332537 | 100% |
Reaction Steps
Methyl 2-[(2,6-dichlorobenzoyl)amino]-3-(4-nitrophenyl)propanoate 7 (7 g) is solubilized in CH3OH in presence of Pt(S)/C (5% in weight). H2 pressure is then applied at RT for 2 h. The catalyst is filtered over celite and the solvent is evaporated to give methyl 3-(4-aminophenyl)-2-[(2,6-dichlorobenzoyl)amino]propanoate 8.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07638630B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-adbdb33a47f144659180ceb5d37f1f8b |
| Source note | uspto-grants-2009_12 |