HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl N-(2,6-dichlorobenzoyl)-3-[2-(2,6-dichlorophenyl)-6-quinolyl]alaninate → 2-{[(2,6-Dichlorophenyl)(ethoxy)methylene]amino}-3-[2-(2,6-dichlorophenyl)-6-quinolinyl]propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl N-(2,6-dichlorobenzoyl)-3-[2-(2,6-dichlorophenyl)-6-quinolyl]alaninate | HCID 10482608 | — |
| Reactant | methyl 3-[2-(2,6-dichlorophenyl)-6-quinolinyl]-2-[({(2S)-1-[(4-methylphenyl)sulfonyl]piperidinyl}carbonyl)amino]propanoate | HCID 68592952 | — |
| Reactant | 3-[2-(2,6-dichlorophenyl)-6-quinolinyl]-2-[({(2S)-1-[(4-methylphenyl)sulfonyl]piperidinyl}carbonyl)amino]propanoic acid | HCID 68594696 | — |
| Product | 2-{[(2,6-Dichlorophenyl)(ethoxy)methylene]amino}-3-[2-(2,6-dichlorophenyl)-6-quinolinyl]propanoic acid | HCID 68593260 | — |
Reaction Steps
Compound 64 is synthesized according to Chem. Pharm. Bull. (1984), 32, (11), 4466-4477 starting from compound 35 followed by basic hydrolysis, as described for the transformation of compound 46 into compound 90.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07638630B2 |
| Source dataset | uspto-grants-2009_12 |
| ORD ID | ord-c307935d95c04d67bcda09e765ae9a9d |
| Source note | uspto-grants-2009_12 |