6-(Benzyloxy)-2-phenoxyquinoline → HCID 24755549, compound

Participants

Reaction Steps

To a solution of 6-(benzyloxy)-2-phenoxyquinoline 13 (0.862 g) in CH3OH (10 ml) is added 10% of palladium on C (10%). The reaction is stirred under H2 at room temperature for 1 night. After filtration on celite and concentration, the residue is purified by silica gel chromatography using AcOEt/petroleum ether 10/90 as eluent to give compound 2-phenoxy-6-quinolinol 14 as an oil.

Provenance & Evidence