Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-(tert-Butyl)-2-(hydroxymethyl)phenol → 5-tert-Butyl-o-cresol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-(tert-Butyl)-2-(hydroxymethyl)phenol | HCID 19690241 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 5-tert-Butyl-o-cresol | HCID 79845 | 97.2% |
반응 단계
A solution of 5-tert-butyl-2-hydroxymethyl-phenol (Intermediate 106, 0.215 g, 1.19 mmol) in ethyl acetate was treated with 5% palladium on carbon (0.04 g) and the resulting reaction mixture was stirred under an atmosphere of hydrogen at ambient temperature for 2.5 h. The reaction mixture was then filtered over a bed of celite and the filtrate was evaporated in vacuo to afford the title compound as a white solid (0.19 g, 97%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07638648B2 |
| 출처 데이터셋 | uspto-grants-2009_12 |
| ORD ID | ord-ea00255de45944b59d5e4584d10a56dc |
| 출처 메모 | uspto-grants-2009_12 |