HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 18695394, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1-Chloro-2,4-difluoro-5-nitrobenzene | HCID 73867 | — |
| Reactant | Glycine ethyl ester, hydrochloride | HCID 2723640 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 18695394 | HCID 18695394 | 7.3% |
Reaction Steps
By using 6.32 g of 5-chloro-2,4-difluoronitrobenzene, 9.91 g of triethylamine, 60 ml of DMF, 60 ml of THF and 4.56 g of glycine ethyl ester hydrochloride, 0.66 g (7%) of N-(4-chloro-5-fluoro-2-nitrophenyl)glycine ethyl ester was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06096743 |
| Source dataset | uspto-grants-2000_08 |
| ORD ID | ord-adbd99a1f0a64ac8bd859b75a59c9234 |
| Source note | uspto-grants-2000_08 |