HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 53838198, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Methyl [(chlorocarbonyl)oxy]acetate | HCID 13397504 | — |
| Reactant | (2-Amino-6-methylphenyl)methanol | HCID 15339417 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 53838198 | HCID 53838198 | 35.1% |
Reaction Steps
Starting from methoxycarbonylmethyl chloroformate (11.7 g), 2-amino-6-methylbenzyl alcohol (10.5 g) and pyridine (6.2 ml) in dichloromethane (230 ml), 6.8 g (20%) of the title compound, m.p. 70-74° C., are obtained according to the procedure indicated in Example C1, after chromatography on silica gel (eluent: ethyl acetate/petroleum ether 50/70=1:1) and crystallization from diisopropyl ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06096758 |
| Source dataset | uspto-grants-2000_08 |
| ORD ID | ord-36c8b2d1f183405ea8444a269413b6d0 |
| Source note | uspto-grants-2000_08 |