Thionyl Chloride → HCID 53648443, compound

Participants

Reaction Steps

Methoxycarbonylmethyl (2-hydroxymethyl-3-methylphenyl)carbamate (6.8 g) is introduced in dichloromethane (60 ml) and treated dropwise with thionyl chloride (3.4 ml). The mixture is then stirred at RT for a further 1 h. The solvent is then distilled off and the residue is treated 2 times with dichloromethane (50 ml each) and the mixture is in each case concentrated again on a rotary evaporator. 7 g (96%) of the title compound of m.p. 114-116° C. are obtained.

Provenance & Evidence