HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dichloroaniline → 2-(3,4-Dichloro-phenylamino)-propionic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dichloroaniline | HCID 7257 | — |
| Reactant | Ethyl pyruvate | HCID 12041 | — |
| Reactant | 2-(3,4-Dichloro-phenylamino)-propionic Acid ethyl ester | HCID 6914808 | — |
| Product | 2-(3,4-Dichloro-phenylamino)-propionic Acid | HCID 6916426 | — |
Reaction Steps
Alternatively, following General Procedure A above and using 3,4-dichloroaniline (Aldrich) and ethyl pyruvate (Aldrich), N-(3,4-dichlorophenyl)-D,L-alanine ethyl ester was prepared as an oil. The reaction was monitored by tlc on silica gel (Rf=0.4 in 25% EtOAc/Hexanes) and purification was by preparative plate chromatography (silica gel using 25% EtOAc/Hexanes as eluent).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06096782 |
| Source dataset | uspto-grants-2000_08 |
| ORD ID | ord-31f09790a74e4635941fe74f1e3574e8 |
| Source note | uspto-grants-2000_08 |