(2S)-2-aminohexanamide → HCID 18341167, compound

HRID 1870326Notes

Reaction equation

HRID 1870326 reaction equation
[NH2:1][C@H:2]([C:7]([NH2:9])=[O:8])[CH2:3][CH2:4][CH2:5][CH3:6].[Cl:10][C:11]1[CH:12]=[C:13]([NH:18][CH:19]([C:21](O)=[O:22])[CH3:20])[CH:14]=[CH:15][C:16]=1[Cl:17]>>[Cl:10][C:11]1[CH:12]=[C:13]([NH:18][C@H:19]([C:21]([NH:9][C:7](=[O:8])[C@@H:2]([NH2:1])[CH2:3][CH2:4][CH2:5][CH3:6])=[O:22])[CH3:20])[CH:14]=[CH:15][C:16]=1[Cl:17]

Participants

3

Reactant 2

HCID 445699(2S)-2-aminohexanamideHCID 69164262-(3,4-Dichloro-phenylamino)-propionic Acid

Product 1

HCID 18341167HCID 18341167, compound

Procedure

Following General Procedure D and using L-norleucine amide (prepared from BOC-L-norleucine amide (from Example F above) using General Procedure F) and N-(3,4-dichlorophenyl)-D,L-alanine, the title compound was prepared as a solid (mp=156-161° C.).

Sources & evidence

ORD record
ord-e40756086b444afcb8b11db5ac7eb0a4
Source dataset
uspto-grants-2000_08
Patent number
US06096782

Reaction notes

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