HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1870357Generated: October 25, 2026
Thionyl Chloride → 3-(2-Fluorocyclopentyloxy)-4-methoxybenzoyl chloride
https://huagongshe.com/reaction/1870357
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-(2-Fluorocyclopentyloxy)-4-methoxybenzoic acid | HCID 21187946 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 3-(2-Fluorocyclopentyloxy)-4-methoxybenzoyl chloride | HCID 21187891 | — |
Reaction Steps
A suspension of 3-(2-fluorocyclopentyloxy)-4-methoxybenzoic acid (0.48 g) in toluene (20 mL) is treated with thionyl chloride (0.34 g) and then is heated at 60° C. for 3 hours, and cooled and evaporated to give 3-(2-fluorocyclopentyl-oxy)-4-methoxybenzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06096768 |
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| Source dataset | uspto-grants-2000_08 |
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| ORD ID | ord-366d8e5cc5bf4192bafb81f036f107d9 |
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| Source note | uspto-grants-2000_08 |
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