Chlorosulfonic acid → HCID 21187901, compound

HRID 1870410Notes

Reaction equation

HRID 1870410 reaction equation
[C:1]([O:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[O:16][CH3:17])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[S:19]([OH:22])(=[O:21])=[O:20]>ClCCl>[C:1]([O:9][C:10]1[CH:15]=[C:14]([S:19]([OH:22])(=[O:21])=[O:20])[CH:13]=[CH:12][C:11]=1[O:16][CH3:17])(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 24638Chlorosulfonic acidHCID 68272Guaiacol benzoate

Product 1

HCID 21187901HCID 21187901, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Conditions

Temperature
2.5 °C

Procedure

A stirred solution of 2-methoxyphenyl benzoate (10 g) in dichloromethane (100 mL) from 0-5° C. is treated dropwise with chlorosulfonic acid (2.9 mL) and the solution is then stirred for 3 hours from 0-5° C. The precipitate which forms is filtered off, washed with cold dichloromethane, and dried in vacuo, to give 3-benzoyloxy-4-methoxybenzenesulfonic acid (11.45 g), in the form of a white solid, m.p. 139-140° C.

Workup

  1. filtrationThe precipitate which forms is filtered off
  2. washwashed with cold dichloromethane
  3. customdried in vacuo

Sources & evidence

ORD record
ord-6bf5b58d9f28412e8e41dafcd631b70f
Source dataset
uspto-grants-2000_08
Patent number
US06096768

Reaction notes

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