反应详情

温度

150 °C

A mixture of 5.0 g 3-(2-hydroxy-phenyl)-acrylic acid ethyl ester, 6.1 g dec-9-en-1-ol and 1.0 g tetraisopropyl-ortho-titanate was heated to 150° C. removing the ethanol formed. After stirring for 2.5 hours at this temperature, the reaction mixture was cooled, diluted with ether and washed with brine. The organic phase was dried and evaporated to dryness. The resulting oil was Kugelrohr-distilled, crystallized and recrystallized to yield 1.69 g of colourless crystals.

1. customremoving the ethanol
2. customformed
3. temperaturethe reaction mixture was cooled
4. washwashed with brine
5. customThe organic phase was dried
6. customevaporated to dryness
7. distillationThe resulting oil was Kugelrohr-distilled
8. customcrystallized
9. customrecrystallized