2-Dimethylaminopyridine → HCID 136149643, compound

Participants

Reaction Steps

To a solution of 8.02 g of the 5-(6-chloro-2,2,4,7-tetramethylindan-5-yl)-cyclohexane-1,3-dione in 100 ml of absolute toluene was added 12.8 ml of propionic anhydride. After refluxing for 4 hours, toluene and excess propionicanhydride were evaporated under reduced pressure to afford a residue. To the solution of the residue in 100 ml of toluene was added 0.61 g of dimethylaminopyridine and refluxed for 20 hours. The reaction mixture was evaporated under reduced pressure. The residue was purified by silica-gel column chromatography to afford 10.1 g of the title compound as yellow solid.

Provenance & Evidence