Toluene → HCID 18696707, compound

Participants

Reaction Steps

To a solution 7.12 g of the 5-(7-chloro-2-ethyl-2,4,5-trimethylindan-6-yl)-cyclohexane-1,3-dione in 70 ml of absolute toluene was added 15 ml of buryric anhydride. After refluxing for 4 hours, toluene and excess butyric anhydride were evaporated under reduced pressure to afford a residue. To the solution of the residue in 100 ml of toluene was added 0.56 g of dimethylaminopyridine and refluxed for 20 hours. The reaction mixture was evaporated under reduced pressure. The residue was purified by silica-gel column chromatography to afford 4.64 g of the title compound as yellow solid.

Provenance & Evidence