HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl isothiocyanate → HCID 18693429, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl isothiocyanate | HCID 68284 | — |
| Reactant | HCID 15676040 | HCID 15676040 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 18693429 | HCID 18693429 | 83.9% |
Reaction Steps
A solution consisting of {3-[1-(2-fluoro-biphenyl-4-yl)-ethyl]-isoxazol-5-yl}-methyl-amine (4.06 g), pyridine (40 ml) and benzoyl isothiocyanate (2.5 g) was stirred overnight at room temperature. The solution was concentrated and the residue was purified by a silica gel column chromatography to obtain the desired compound (5.28 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06100260 |
| Source dataset | uspto-grants-2000_08 |
| ORD ID | ord-3c540f757dcc47daa9ff3d4e84d2a4cb |
| Source note | uspto-grants-2000_08 |