HCID 18694226, compound → HCID 18694248, compound

HRID 1870884Notes

Reaction equation

HRID 1870884 reaction equation
Cl[CH2:2][CH2:3][NH:4][C:5]([NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([O:22][CH3:23])=[O:21])=[CH:16][CH:15]=2)=[C:10]([CH3:24])[CH:9]=1)=[O:6]>O>[O:6]=[C:5]1[NH:4][CH2:3][CH2:2][N:7]1[C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([O:22][CH3:23])=[O:21])=[CH:16][CH:15]=2)=[C:10]([CH3:24])[CH:9]=1

Participants

3

Reactant 1

HCID 18694226HCID 18694226, compound

Product 1

HCID 18694248HCID 18694248, compoundYield 90%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

This was prepared from N-(2-chloroethyl)-N'-(4'-methoxycarbonyl-2-methylbiphenyl-4-yl)urea (D17), following the procedure of Description 4. The product was isolated by dilution of the reaction mixture with water, filtration and drying. This gave the title compound as a cream solid (90%).

Workup

  1. customdrying

Sources & evidence

ORD record
ord-777f368b2df04f83a9bc83c8a9f74b0b
Source dataset
uspto-grants-2000_08
Patent number
US06100272

Reaction notes

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